Thermo Fisher Scientific TBX5 Polyclonal Antibody
TBX5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. 인간 및 생쥐 시료에서 반응하며, WB, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 4 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 4 publications |
| Immunoprecipitation (IP) | Assay-dependent | View 2 publications |
| ChIP assay (ChIP) | - | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from an internal region of the human, predicted dog, and predicted chimpanzee Tbx5 proteins, differing from mouse and rat by one conservative amino acid change |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533533 |
Target Information
The TBX5 gene belongs to a phylogenetically conserved family of genes sharing a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in developmental regulation. TBX5 is closely linked to T-box 3 (associated with ulnar mammary syndrome) on human chromosome 12. The protein plays a role in heart development and limb identity specification. Mutations in TBX5 are associated with Holt-Oram syndrome, affecting heart and upper limb formation. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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