Thermo Fisher Scientific Villin (GI-Mucosal and Urogenital Brush Border Marker) Monoclonal Antibody (VIL1/2376)
인체 Villin 단백질을 인식하는 단클론 항체로, 위장관 및 비뇨생식계 브러시 보더 마커 연구에 적합. IHC 및 ELISA에서 사용 가능하며, Protein A/G 정제 및 4°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIL1/2376 |
| Immunogen | A recombinant fragment (around aa 179–311) of human Villin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Villin is part of the cytoskeleton associated with the microvillar actin core bundle of the gastrointestinal and renal brush border. It can interact with actin in a Ca²⁺ and phosphoinositide-regulated manner. Villin serves as a specific marker for adenocarcinomas of the gastrointestinal tract and pancreas, and is also expressed in some Merkel cell tumors and adenocarcinomas of the lung, prostate, ovary, and kidney.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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