Thermo Fisher Scientific CCR7 Monoclonal Antibody (1987CT875.52.22)
인간 CCR7 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. KLH 결합 합성 펩타이드 면역원으로 제작되었으며, 단백질 G로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1987CT875.52.22 |
| Immunogen | KLH conjugated synthetic peptide between 26–57 amino acids from the N-terminal region of human CCR7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897690 |
Target Information
CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. It is induced by Epstein Barr virus (EBV) and mediates EBV effects on B lymphocytes. CCR7 is expressed in blood, bone marrow, lymph node, and intestine, particularly in lymphoid tissues and activated B and T lymphocytes. It controls migration of memory T cells to inflamed tissues and stimulates dendritic cell maturation. The chemokine ligand CCL19/ECL is a specific ligand for this receptor. CCR7 and other C-C chemokine receptors (CCR1, CCR2A, CCR3, CCR4, CCR5, Duffy antigen) play roles in T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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