Thermo Fisher Scientific MLLT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.4 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human MLLT1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2608141

Product Specific Information

Peptide sequence: EESNSEDEAS FKSESAQSSP SNSSSSSDSS SDSDFEPSQN HSQGPLRSMV

Sequence homology: Cow: 93%; Dog: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rat: 100%

Target Information

Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.