Thermo Fisher Scientific MLLT1 Polyclonal Antibody
Thermo Fisher Scientific의 MLLT1 Polyclonal Antibody는 인간 MLLT1 단백질을 인식하는 토끼 IgG 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, Protein A 정제 및 PBS 저장 완충액에 보관됩니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MLLT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608141 |
Product Specific Information
Peptide sequence:
EESNSEDEAS FKSESAQSSP SNSSSSSDSS SDSDFEPSQN HSQGPLRSMV
Sequence homology:
- Cow: 93%
- Dog: 93%
- Human: 100%
- Mouse: 93%
- Pig: 93%
- Rat: 100%
Target Information
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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