Thermo Fisher Scientific Caspase 3 Polyclonal Antibody
Caspase 3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도(0.5 mg/mL) 액상 형태로 제공됩니다. 세포사멸 연구 및 신경퇴행성 질환 관련 연구에 유용합니다.
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- PA5119004
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.01–5 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Caspase 3 (amino acids 29–175 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903504 |
Target Information
The Caspase 3 gene encodes a cysteine-aspartic acid protease that plays a central role in the execution phase of cell apoptosis. Caspases are synthesized as inactive proenzymes and become active through proteolytic processing. Caspase 3 cleaves and activates caspases 6, 7, and 9, and is itself processed by caspases 8, 9, and 10. It is the predominant caspase involved in cleavage of amyloid-beta 4A precursor protein, associated with neuronal death in Alzheimer’s disease. Alternative splicing produces two transcript variants encoding the same protein.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
- PA5-119004_Caspase_3_P42574-1_Rabbit.svg
- PA5-119004_Caspase_3_P42574-1_Rabbit_PDP.jpeg
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