Thermo Fisher Scientific THAP1 Polyclonal Antibody, MaxPab
THAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 액상 형태로 제공되며 PBS buffer에 보관. 세포 주기 조절 및 전사 활성 연구용.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | THAP1 (NP_060575.1, 1–213 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVQSCSAYGC KNRYDKDKPV SFHKFPLTRP SLCKEWEAAV RRKNFKPTKY SSICSEHFTP DCFKRECNNK LLKENAVPTI FLCTEPHDKK EDLLEPQEQL PPPPLPPPVS QVDAAIGLLM PPLQTPVNLS VFCDHNYTVE DTMHQRKRIH QLEQQVEKLR KKLKTAQQRC RRQERQLEKL KEVVHFQKEK DDVSERGYVI LPNDYFEIVE VPA
Target Information
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and modulates expression of pRB-E2F cell-cycle target genes, including RRM1.
Component of a THAP1/THAP3-HCFC1-OGT complex, required for regulation of RRM1 transcriptional activity.
May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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