Thermo Fisher Scientific IKZF3 Polyclonal Antibody
IKZF3(Aiolos) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. Human 및 Mouse 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 용액 형태로 제공되며, 4°C 또는 -20°C에서 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 76–103 amino acids from the central region of human IKZF3 (Aiolos, UniProt ID: Q9UKT9-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543064 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos, and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor important for B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos involves sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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