Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1D10)
IL10RA 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 인간 IL10RA 전체 길이 재조합 단백질을 면역원으로 사용하였으며, 액상 형태로 1 mg/mL 농도입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D10 |
| Immunogen | Full length human recombinant protein of IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724515 |
Target Information
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It mediates the immunosuppressive signal of interleukin 10, inhibiting synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and one non-protein-coding, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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