Thermo Fisher Scientific RAB12 Polyclonal Antibody
RAB12 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC(P)에서 검증됨. 인간과 생쥐 시료에 반응하며, 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB12 (Accession Q6IQ22), corresponding to amino acid residues L210–C244 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815704 |
Product Specific Information
Antibody detects endogenous levels of total RAB12.
Target Information
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors responsible for vesicle formation, movement, tethering, and fusion. RAB12 may play a role in protein transport from recycling endosomes to lysosomes, regulating degradation of the transferrin receptor and being involved in autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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