Thermo Fisher Scientific LRRTM4 Polyclonal Antibody
LRRTM4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 사람과 설치류에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도의 Affinity Chromatography 정제 제품으로 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human LRRTM4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606984 |
Product Specific Information
Peptide sequence:
FYWLKNFKGN KESTMICAGP KHIQGEKVSD AVETYNICSE VQVVNTERSH
Sequence homology:
Cow: 93%
Dog: 100%
Guinea Pig: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 79%
Target Information
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation.
Little is known about the function of LRRTM4; in mouse, it is expressed in the limb mesenchyme, neural tube, caudal mesoderm, and in three distinct regions of the head. Later expression occurs in a subset of the developing sclerotome.
Its similarity to other LRRTM family members suggests that LRRTM4 may also play a role in the development and maintenance of the vertebrate nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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