Thermo Fisher Scientific CRMP5 Polyclonal Antibody
CRMP5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관됩니다. 신경 발달 및 종양 관련 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DPYSL5. Recombinant protein control fragment (Product #RP-105561) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792045 |
Product Specific Information
Immunogen sequence:
CPIYLVNVSS ISAGDVIAAA KMQGKVVLAE TTTAHATLTG LHYYHQDWSH AAAYVTVPPL RLDTNTSTYL MSLLANDTLN IVASDH
Target Information
The collapsin response mediator protein (CRMP) family (also known as ULIP6) are neurologic proteins involved in growth cone guidance during neural development.
CRMP5 shows relatively low sequence homology with other CRMP family members and is expressed in the developing nervous system, peaking during the first postnatal week.
Elevated levels of autoantibodies to CRMP5 have been associated with paraneoplastic autoimmune optic neuritis and other paraneoplastic syndromes.
Auto-immunity against CRMP5 (particularly N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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