Thermo Fisher Scientific CCR1 Polyclonal Antibody
CCR1 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, ICC/IF, IP)에 사용 가능. 인간 종에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS 용액 형태로 제공되며 보존제가 없음. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 | - |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of Human CCR1/CD191 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866794 |
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein-coupled receptors. The chemokine receptor subtypes are divided into two major groups, CXCR and CCR. CCR1 is expressed on neutrophils, monocytes, lymphocytes, and eosinophils, and binds macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines. Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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