Thermo Fisher Scientific CD80 Monoclonal Antibody (8B9)
Thermo Fisher Scientific의 CD80 Monoclonal Antibody (Clone 8B9)는 인간 CD80 단백질을 인식하는 마우스 IgG1 항체로, Western blot 및 ELISA에 사용됩니다. PBS 기반 액상 형태이며, 항원 제시 세포의 CD80/B7-1 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8B9 |
| Immunogen | CD80 (AAH11399.2, 137 a.a. ~ 230 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
SVKADFPTPS ISDFEIPTSN IRRIICSTSG GFPEPHLSWL ENGEELNAIN TTVSQDPETE LYAVSSKLDF NMTTNHSFMC LIKYGHLRVN QTFNTarget Information
CD80 (B7-1) and CD86 (B7-2) are ligands of the T cell costimulatory molecule CD28 and the inhibitory receptor CTLA-4 (CD152).
Both molecules are expressed on professional antigen-presenting cells and are essential for T cell activation.
CD80 is rapidly induced on the surface of activated B cells, EBV-transformed B cell lines, Burkitt lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes.
The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes through binding to CD28 and CTLA4 ligands.
Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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