Thermo Fisher Scientific ID3 Polyclonal Antibody
ID3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드 유래 항원 사용, 친화 크로마토그래피로 정제. PBS/glycerol buffer에 보관, -20°C 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ID3 (Accession Q02535), corresponding to amino acid residues S21–Q71 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815798 |
Product Specific Information
Antibody detects endogenous levels of total ID3.
Target Information
Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3, and ID4. They are ubiquitously expressed and form heterodimers with class A and B HLH proteins. Due to the absence of the basic region, these heterodimers cannot bind DNA, thus acting as negative regulators of bHLH protein DNA binding. ID proteins modulate differentiation processes such as muscle-specific gene expression by controlling the availability of DNA-binding bHLH dimers. Expression of ID proteins is growth factor-dependent, and reduction of ID mRNA delays cell cycle reentry following growth factor stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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