Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간 MSI2 단백질(250-300 aa)에 특이적.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 250 and 300 of human Musashi Homolog 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Msi2 (Musashi homolog 2), also known as MSI2H, is a 328 amino acid cytoplasmic RNA-binding protein containing two RRM (RNA recognition motif) domains. It is expressed ubiquitously at low levels and regulates target mRNA expression, playing a role in stem cell proliferation and maintenance in the central nervous system. Msi2 is phosphorylated posttranslationally and upregulated in response to brain injury, suggesting involvement in tissue regeneration. Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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