Thermo Fisher Scientific LNK Polyclonal Antibody
인간 SH2B3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 고순도 Affinity chromatography 정제, 액상 형태로 1 mg/mL 농도. -20°C 보관, 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SH2B3 (Accession Q9UQQ2), corresponding to amino acid residues M1–H33 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853462 |
Product Specific Information
Antibody detects endogenous levels of total SH2B3.
Target Information
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors.
The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis.
Mutations in this gene have been associated with susceptibility to celiac disease type 13 and insulin-dependent diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-104134_LNK_Q9UQQ2-1_Rabbit.svg, PA5-104134_LNK_Q9UQQ2-1_Rabbit_PDP.jpeg)
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