ELK Biotechnology BMP-4 rabbit pAb
BMP-4 rabbit pAb는 인간 BMP-4 유래 펩타이드로부터 제작된 폴리클로날 항체로 WB 및 ELISA에 적합합니다. TGF-beta 계열 단백질 검출에 활용되며, 뼈 및 연골 형성 관련 연구에 유용합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology BMP-4 rabbit pAb
제품명
BMP-4 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Bone morphogenetic protein 4 (BMP-4; Bone morphogenetic protein 2B; BMP-2B) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:1000–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human BMP-4 (AA range: 261–310) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 652 |
| Human Swiss-Prot No. | P12644 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Species Reactivity | Human; Rat; Mouse |
Background
Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932], also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies.
Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia).
In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities.
MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic, and endocrine anomalies.
Function: Induces cartilage and bone formation. Also acts in mesoderm induction, tooth development, limb formation, and fracture repair.
Similarity: Belongs to the TGF-beta family.
Subunit: Homodimer; disulfide-linked (By similarity). Interacts with GREM2 and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.
Tissue Specificity: Expressed in the lung; lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.