ELK Biotechnology Integrin αIIb rabbit pAb
Integrin αIIb rabbit polyclonal antibody for WB and ELISA applications. Recognizes human, rat, and mouse integrin αIIb. Derived from human peptide (AA 1–80), stored at −20°C. Suitable for platelet aggregation and coagulation research.
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Integrin αIIb Rabbit Polyclonal Antibody
제품 개요
Integrin αIIb rabbit pAb는 혈소판 응집 및 혈액 응고 시스템 연구에 사용되는 항체로, 인간 Integrin αIIb에서 유래한 합성 펩타이드(AA 1–80)를 면역원으로 제작되었습니다. WB 및 ELISA 분석에 적합하며, 인간, 랫드, 마우스 시료에서 반응합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | Integrin αIIb rabbit pAb |
| Alternative Names | Integrin alpha-IIb (GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2] |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human Integrin αIIb (AA range: 1–80) |
| Host | Rabbit |
| Storage | −20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 3674 |
| Human Swiss-Prot No | P08514 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. (RefSeq, Jan 2016)
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