ELK Biotechnology Pdcd-1 rabbit pAb
인간 Pdcd-1 단백질을 인식하는 토끼 폴리클로날 항체로 WB, ELISA, IHC에 적합. 높은 특이성과 재현성을 제공하며 세포막 단백질 분석에 활용 가능. -20°C에서 1년 보관 가능.
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Pdcd-1 rabbit pAb
제품 개요
Pdcd-1 rabbit pAb는 인간 Pdcd-1 단백질을 인식하는 토끼 유래 폴리클로날 항체로, 세포막 단백질 연구 및 면역학적 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Pdcd-1 rabbit pAb |
| Alternative Names | Programmed cell death protein 1 (Protein PD-1; hPD-1; CD antigen CD279) |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 2000–20000 |
| Immunogen | Synthesized peptide derived from human Pdcd-1 (AA range: 80–130) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 5133 |
| Human Swiss-Prot No | Q15116 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. It is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
[provided by RefSeq, Jul 2008]
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