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ELK Biotechnology Dab1 (Phospho Tyr220) rabbit pAb
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ELK Biotechnology Dab1 (Phospho Tyr220) rabbit pAb

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Dab1 (Phospho Tyr220) rabbit polyclonal antibody로 신경 발달 관련 단백질 Dab1의 인산화 형태를 검출. WB 및 ELISA에 적합하며, 높은 특이성과 재현성을 제공. 인간, 마우스, 랫트 시료에 반응.

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pk
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ELK Biotechnology ES20203-100UL Dab1 (Phospho Tyr220) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES20203-50UL Dab1 (Phospho Tyr220) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Dab1 (Phospho Tyr220) rabbit pAb

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Dab1 (Phospho Tyr220) rabbit pAb

제품 정보

항목 내용
Alternative Names Disabled homolog 1
Applications WB; ELISA
Recommended Dilutions WB 1:1000–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from human Dab1 (Phospho Tyr220)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 60 kD
Gene ID (Human) 1600
Human Swiss-Prot No. O75553
Species Reactivity Human; Mouse; Rat

Background

  • Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
  • Function: Adapter molecule functioning in neural development; may regulate SIAH1 activity.
  • Post-translational Modification (PTM): Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (by similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
  • Similarity: Contains one PID domain.
  • Subunit: Associates with the SH2 domains of SRC, FYN, and ABL. Interacts with DAB2IP and SIAH1 (by similarity). Also interacts with LRP1.

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