ELK Biotechnology SRC-1 (Phospho Thr1179) rabbit pAb
SRC-1 (Phospho Thr1179) rabbit pAb는 인간 및 생쥐 SRC-1 인산화 단백질을 검출하는 폴리클로날 항체입니다. WB 및 ELISA에 적합하며, 핵 내 전사 조절 연구에 활용됩니다. 고순도의 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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SRC-1 (Phospho Thr1179) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | SRC-1 (Phospho Thr1179) rabbit pAb |
| Alternative Names | Nuclear receptor coactivator 1 (NCoA-1; EC 2.3.1.48; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human SRC-1 (Phospho Thr1179) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 158 kDa |
| GeneID (Human) | 8648 |
| Human Swiss-Prot No | Q15788 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and, like other family members, has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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