ELK Biotechnology Tubulin α (Acetyl Lys401) rabbit pAb
Tubulin α (Acetyl Lys401) rabbit polyclonal antibody로 WB 및 ELISA에 적합. 인간, 마우스, 랫트 반응성. 세포질 및 세포골격에 위치한 α-튜불린 인식. 고순도 IgG, -20°C에서 1년 보관 가능.
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제품명
Tubulin α (Acetyl Lys401) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Tubulin alpha-1A chain (Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human Tubulin α (Acetyl Lys401) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| Gene ID (Human) | 7846 |
| Human Swiss-Prot No. | Q71U36 / P68363 / Q9BQE3 / Q13748 / P68366 / Q9NY65 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
Background
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which includes six distinct families. Genes from the alpha, beta, and gamma tubulin families are found in all eukaryotes.
Alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. Multiple alpha and beta tubulin genes are highly conserved among species.
This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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