ELK Biotechnology NCoA-3 (Acetyl Lys616) rabbit pAb
NCoA-3 (Acetyl Lys616) rabbit pAb는 인간, 랫드, 마우스에 반응하는 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 핵 수용체 공동활성화 단백질을 인식하며, 세포질과 핵에서 발현됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
NCoA-3 (Acetyl Lys616) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Nuclear receptor coactivator 3 (NCoA-3; EC 2.3.1.48; ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42; bHLHe42; Receptor-associated coactivator 3; RAC-3; Steroid receptor coactivator protein 3; SRC-3; Thyroid hormone receptor activator molecule 1; TRAM-1) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human NCoA-3 (Acetyl Lys616) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 160 kD |
| Gene ID (Human) | 8202 |
| Human Swiss-Prot No. | Q9Y6Q9 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Cytoplasm and nucleus. Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus. |
Background
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but translocates into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
[Provided by RefSeq, Mar 2010]
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