ELK Biotechnology Histone H2A (Acetyl Lys120) rabbit pAb
Histone H2A (Acetyl Lys120) rabbit polyclonal antibody로, 인간, 마우스, 랫트 시료에 반응합니다. WB 및 ELISA에 사용 가능하며, 고순도 IgG 형태로 제공됩니다. 핵 및 염색체 내 단백질 검출에 적합합니다.
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제품명
Histone H2A (Acetyl Lys120) rabbit pAb
제품 개요
Histone H2A (Acetyl Lys120)은 핵 내 염색질 구조 형성에 관여하는 기본 단백질입니다. 본 항체는 인간 Histone H2A (Acetyl Lys120)에서 유래한 합성 펩타이드를 면역원으로 제작된 토끼 다클론 항체로, WB 및 ELISA 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A (Acetyl Lys120) rabbit pAb |
| Alternative Names | Histone H2A type 1 (H2A.1; Histone H2A/p) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human Histone H2A (Acetyl Lys120) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kDa |
| Gene ID (Human) | 8329 |
| Human Swiss-Prot No. | P0C0S8 / P16104 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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