Thermo Fisher Scientific TSN Monoclonal Antibody (OTI4C6)
TSN 단백질(Translin)을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 인간 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS 기반 저장용액에 BSA, 글리세롤, sodium azide가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of TSN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725591 |
Target Information
Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may indicate breakpoints in genes fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that, in combination with its binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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