Thermo Fisher Scientific JAKMIP2 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF)
  Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
RETEKQCKPLL ERNKCLAKRN DELMVSLQRM EEKLKAVTKE NSEMREKITS HPPLKKLKSL NDLDQANEEQ

Highest antigen sequence identity to the following orthologs:

• Mouse: 100%
• Rat: 99%

Target Information

JAKMIP2 (Janus kinase and microtubule-interacting protein 2), also known as NECC1 (neuroendocrine long coiled-coil protein 1), CTCL tumor antigen HD-CL-04, JAMIP2, or KIAA0555, is an 810 amino acid protein belonging to the JAKMIP family.
Localizes to the Golgi apparatus and is highly expressed in the brain, with moderate expression in thymus, spleen, and lung.
Exists as three alternatively spliced isoforms. The gene encoding JAKMIP2 maps to human chromosome 5q32 and mouse chromosome 18 B3.
Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome.
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.