Thermo Fisher Scientific Gelsolin Recombinant Rabbit Monoclonal Antibody (0N10G5)
Gelsolin 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 고순도 친화 크로마토그래피로 정제되었습니다. 인체 Gelsolin(aa 28-782) 항원 서열 기반으로 제작되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 0N10G5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 28–782 of human Gelsolin (NP_000168.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.07 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093021 |
Product Specific Information
Immunogen sequence:
ATASRGASQA GAPQGRVPEA RPNSMVVEHP EFLKAGKEPG LQIWRVEKFD LVPVPTNLYG DFFTGDAYVI LKTVQLRNGN LQYDLHYWLG NECSQDESGA AAIFTVQLDD YLNGRAVQHR EVQGFESATF LGYFKSGLKY KKGGVASGFK HVVPNEVVVQ RLFQVKGRRV VRATEVPVSW ESFNNGDCFI LDLGNNIHQW CGSNSNRYER LKATQVSKGI RDNERSGRAR VHVSEEGTEP EAMLQVLGPK PALPAGTEDT AKEDAANRKL AKLYKVSNGA GTMSVSLVAD ENPFAQGALK SEDCFILDHG KDGKIFVWKG KQANTEERKA ALKTASDFIT KMDYPKQTQV SVLPEGGETP LFKQFFKNWR DPDQTDGLGL SYLSSHIANV ERVPFDAATL HTSTAMAAQH GMDDDGTGQK QIWRIEGSNK VPVDPATYGQ FYGGDSYIIL YNYRHGGRQG QIIYNWQGAQ STQDEVAASA ILTAQLDEEL GGTPVQSRVV QGKEPAHLMS LFGGKPMIIY KGGTSREGGQ TAPASTRLFQ VRANSAGATR AVEVLPKAGA LNSNDAFVLK TPSAAYLWVG TGASEAEKTG AQELLRVLRA QPVQVAEGSE PDGFWEALGG KAAYRTSPRL KDKKMDAHPP RLFACSNKIG RFVIEEVPGE LMQEDLATDD VMLLDTWDQV FVWVGKDSQE EEKTEALTSA KRYIETDPAN RDRRTPITVV KQGFEPPSFV GWFLGWDDDY WSVDPLDRAM AELAA
Target Information
The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. This calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene cause familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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