Thermo Fisher Scientific Monoamine Oxidase B Polyclonal Antibody
Monoamine Oxidase B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. 인간과 마우스를 포함한 다양한 종에 반응. 고순도 Affinity Chromatography 정제, 액상 형태로 제공되며 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human MAOB (aa 36–85) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609083 |
Product Specific Information
Peptide sequence:
RDRVGGRTYT LRNQKVKYVD LGGSYVGPTQ NRILRLAKEL GLETYKVNEVSequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 100%
Pig: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 79%
Target Information
MAOB (Monoamine Oxidase B), also known as MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein encoded by the MAOB gene in humans.
MAOB is a member of the flavin monoamine oxidase family and is mapped on Xp11.3. It catalyzes the oxidative deamination of biogenic and xenobiotic amines, playing an essential role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.
This protein preferentially degrades benzylamine and phenylethylamine, and also degrades dopamine.
MAO-B inhibition is associated with enhanced dopamine activity and reduced hydrogen peroxide production, thus lowering reactive oxygen species formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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