Thermo Fisher Scientific MAPK6 Monoclonal Antibody (4C11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

4C11

Immunogen

MAPK6 (AAH35492, 612 a.a. approximately 721 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERK3,uniProtId:Q16659-1,ncbiNodeId:9606,antigenRange:612-721,antigenLength:721,antigenImageFileName:H00005597-M02_ERK3_Q16659-1_House_mouse.svg,antigenImageFileNamePDP:H00005597-M02_ERK3_Q16659-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EVRKDEQVEK ENTYTSYLDK FFSRKEDTEM LETEPVEDGK LGERGHEEGF LNNSGEFLFN KQLESIGIPQ FHSPVGSPLK SIQATLTPSA MKSSPQIPHQ TYSSILKHLN

Target Information

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.