Thermo Fisher Scientific MAPK6 Monoclonal Antibody (4C11)
MAPK6 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal antibody(4C11). Western blot, ICC/IF, ELISA에 사용 가능하며 Human, Mouse, Rat에 반응. Affinity chromatography로 정제된 액상 항체로, PBS(pH 7.4) buffer에 보존.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C11 |
| Immunogen | MAPK6 (AAH35492, 612–721 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
EVRKDEQVEK ENTYTSYLDK FFSRKEDTEM LETEPVEDGK LGERGHEEGF LNNSGEFLFN KQLESIGIPQ FHSPVGSPLK SIQATLTPSA MKSSPQIPHQ TYSSILKHLN
Target Information
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), are activated through phosphorylation cascades and serve as integration points for multiple biochemical signals.
This kinase localizes to the nucleus and is activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in skeletal muscle, followed by brain. Also found in heart, placenta, lung, liver, pancreas, kidney, and skin fibroblasts.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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