Thermo Fisher Scientific CERKL Polyclonal Antibody
Rabbit polyclonal antibody specific for human CERKL protein. Validated for ICC/IF with high specificity. Suitable for studying CERKL-related retinal diseases. Supplied in liquid form with antigen affinity purification. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CERKL. Recombinant protein control fragment (Product #RP-104662) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663456 |
Product Specific Information
Immunogen sequence:
RNRVSALEGGR EEEAPPEAAA VPPALLTSPQ QTEAAAERIL LRGIFEIGRD SCDVVLSERA LRWRPIQPER PAGDSKYDLL CKEEFIELKD
- Highest antigen sequence identity to orthologs: mouse 57%, rat 51%
Target Information
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP). It encodes a protein with ceramide kinase-like domains but does not phosphorylate ceramide, and its substrate remains unknown. The protein may act as a negative regulator of apoptosis in photoreceptor cells. Mutations cause autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing results in multiple transcript variants and non-coding transcripts.
[Provided by RefSeq, May 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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