Thermo Fisher Scientific RANBP1 Monoclonal Antibody (OTI8E1)
RANBP1 단백질을 인식하는 Mouse IgG2b 단클론 항체로 인간 시료에 반응합니다. Western blot에 1:500~1:2,000 희석 비율로 사용 가능하며, 액상 형태로 제공됩니다. PBS 기반 저장용액에 BSA와 glycerol 포함, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E1 |
| Immunogen | Full length human recombinant protein of RANBP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725189 |
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN. The RANBP1 gene encodes a 23 kDa protein that binds RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but enhances GTP hydrolysis by RanGAP1. The encoded 201-amino acid protein shares 92% similarity with its mouse homolog. In mammalian and yeast cells, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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