Thermo Fisher Scientific Tyrosinase (Melanoma Marker) Monoclonal Antibody (SPM360)
멜라노마 마커인 Tyrosinase를 검출하는 Mouse Monoclonal Antibody로, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 Protein A/G 정제, 보존제 무첨가 PBS 용액 형태.
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Thermo Fisher Scientific Tyrosinase (Melanoma Marker) Monoclonal Antibody (SPM360)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM360 |
| Immunogen | Recombinant tyrosinase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Tyrosinase catalyzes the initial steps in melanin biosynthesis, converting tyrosine to melanin. It has both tyrosine hydroxylase and dopa oxidase activities and requires copper for function. Mutations cause oculocutaneous albinism, while polymorphisms influence skin pigmentation. The human genome also includes a pseudogene related to the 3′ half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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