Thermo Fisher Scientific MSL1 Polyclonal Antibody
MSL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 ELISA에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity Chromatography로 정제된 액상 시약입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 210–300 of human MSL1 (NP_001012241) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855397 |
Product Specific Information
Immunogen sequence:
LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S
Target Information
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at Lys-16 (H4K16ac), which is implicated in the formation of higher-order chromatin structure (PubMed:16227571).
Enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at Lys-34 (H2BK34Ub) (PubMed:21726816).
This modification stimulates histone H3 methylation at Lys-4 (H3K4me) and Lys-79 (H3K79me), leading to gene activation, including HOXA9 and MEIS1 (PubMed:21726816).
In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation (PubMed:22547026). [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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