Thermo Fisher Scientific NMDAR2C Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMDAR2C (GRIN2C). Validated for WB and IHC with dilution 1:300–1:2,000. Lyophilized form, reconstitute in sterile water. Ideal for neuroscience research on NMDA receptor function and CNS disorders.
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- OSN00038W-100UL
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from 2d cytoplasmic domain of human NMDAR2C (GRIN2C) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: NMDAR2C.
Target Information
The NMDA Receptor (NMDAR) plays a crucial role in memory and neuronal development, and is implicated in several central nervous system disorders such as Alzheimer’s disease, epilepsy, and ischemic neuronal cell death. It is also a principal molecular target for alcohol in the CNS and is potentiated by protein phosphorylation. The NR1 protein can form NMDA-activated channels when expressed in Xenopus oocytes, though with smaller currents than in situ. Physiological channel characteristics are achieved when the NR1 subunit combines with one or more of the NMDAR2 (NR2 A–D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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