Thermo Fisher Scientific MCP-1 Recombinant Rabbit Monoclonal Antibody (7Y7F4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:9,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7Y7F4

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-99 of human CCL2/MCP-1(NP_002973.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCL2 (MCP-1),uniProtId:P13500-1,ncbiNodeId:9606,antigenRange:22-99,antigenLength:99,antigenImageFileName:MA5-51310_CCL2_MCP-1_P13500-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51310_CCL2_MCP-1_P13500-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093111

Product Specific Information

Immunogen sequence: LAQPDAINAP VTCCYNFTNR KISVQRLASY RRITSSKCPK EAVIFKTIVA KEICADPKQK WVQDSMDHLD KQTQTPKT

Target Information

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.