Thermo Fisher Scientific Noradrenaline Transporter (NET) (extracellular) Polyclonal Antibody
Noradrenaline Transporter(NET) 단백질의 세포외 영역을 인식하는 토끼 폴리클로날 항체로, WB, IHC(F), ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 마우스와 랫트 시료에 반응.
- 카탈로그번호
- AMT-002-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Noradrenaline Transporter (NET) (extracellular) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KLLNASVLGDHTKYSK, corresponding to amino acid residues 189–204 of mouse NET (2nd extracellular loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature. Store at -20°C upon arrival.
- Reconstituted solution can be stored at 4°C for up to 1 week. For long-term storage, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Norepinephrine Transporter (NET, or noradrenaline transporter, NAT) is a monoamine transporter responsible for returning the neurotransmitter noradrenaline from the synapse back to storage vesicles. It can also transport dopamine to a lesser extent.
Reduced NET levels have been observed in the locus coeruleus of patients with major depression. Cocaine, amphetamines, and antidepressants such as SNRIs and TCAs act to increase noradrenaline levels.
Mutations or deficits in the NET gene have been associated with ADHD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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