Thermo Fisher Scientific Reelin Polyclonal Antibody
Reelin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC(F), ICC/IF에 사용 가능하며 Mouse, Rat 반응성. Protein A 정제, PBS/glycerol buffer, 4°C 단기·-20°C 장기 보관. 뇌 조직 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of mouse Reelin. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736514 |
Product Specific Information
- Positive Control: mouse brain, rat brain
- Predicted Reactivity: Human (97%), Chicken (91%), Sheep (98%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Reelin is an extracellular matrix serine protease that plays a role in the layering of neurons in the cerebral cortex and cerebellum. It regulates microtubule function in neurons and neuronal migration. Reelin affects migration of sympathetic preganglionic neurons in the spinal cord, acting as a barrier to neuronal migration. Its enzymatic activity modulates cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-78413_Reelin_Q60841-1_Rabbit.svg, PA5-78413_Reelin_Q60841-1_Rabbit_PDP.jpeg)
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