Thermo Fisher Scientific GSTM4 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the mu class. The mu class of enzymes functions in detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products through conjugation with glutathione.
Genes encoding mu class enzymes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to toxins and drug efficacy. Multiple transcript variants encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.