Thermo Fisher Scientific PTF1A Monoclonal Antibody (1A2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1A2

Immunogen

PTF1A (NP_835455, 250 a.a. approximately 328 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTF1A,uniProtId:Q7RTS3-1,ncbiNodeId:9606,antigenRange:250-328,antigenLength:328,antigenImageFileName:H00256297-M05_PTF1A_Q7RTS3-1_House_mouse.svg,antigenImageFileNamePDP:H00256297-M05_PTF1A_Q7RTS3-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: QAQKVIICHR GTRSPSPSDP DYGLPPLAGH SLSWTDEKQL KEQNIIRTAK VWTPEDPRKL NSKSSFNNIE NEPPFEFVS

Target Information

PFT1A is a component of the pancreas transcription factor 1 complex and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.