Thermo Fisher Scientific PHGDH Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.
• For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
• Based on 100% sequence identity, this antibody is predicted to react with Bovine, Pig, Orangutan, and Chimpanzee.

Target Information

The PHGDH gene encodes the enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is essential for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants have been identified, though the full-length nature of most is unknown.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.