Thermo Fisher Scientific HDAC4 Monoclonal Antibody (OTI7E1), TrueMAB
HDAC4 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에서 1:2,000 희석으로 검증됨. 인간 HDAC4 전장 재조합 단백질을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E1 |
| Immunogen | Full length human recombinant protein of human HDAC4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation provides a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. HDAC4 acts via the formation of large multiprotein complexes and is involved in muscle maturation through interaction with myocyte enhancer factors MEF2A, MEF2C, and MEF2D. It also participates in MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations in HDAC4 have been associated with Brachydactyly-mental retardation syndrome (BDMR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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