Thermo Fisher Scientific IMP-2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

IMP-2 (AAH21290.1, 1 a.a. approximately 598 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IGF2BP2,uniProtId:Q9Y6M1-2,ncbiNodeId:9606,antigenRange:1-599,antigenLength:599,antigenImageFileName:H00010644-B01P_IGF2BP2_Q9Y6M1-2_House_mouse.svg,antigenImageFileNamePDP:H00010644-B01P_IGF2BP2_Q9Y6M1-2_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MNKLYIGNLS PAVTADDLRQ LFGDRKLPLA GQVLLKSGYA FVDYPDQNWA IRAIETLSGK VELHGKIMEV DYSVSKKLRS RKIQIRNIPP HLQWEVLDGL LAQYGTVENV EQVNTDTETA VVNVTYATRE EAKIAMEKLS GHQFENYSFK ISYIPDEEVS SPSPPQRAQR GDHSSREQGH APGGTSQARQ IDFPLRILVP TQFVGAIIGK EGLTIKNITK QTQSRVDIHR KENSGAAEKP VTIHATPEGT SEACRMILEI MQKEADETKL AEEIPLKILA HNGLVGRLIG KEGRNLKKIE HETGTKITIS SLQDLSIYNP ERTITVKGTV EACASAEIEI MKKLREAFEN DMLAVNQQAN LIPGLNLSAL GIFSTGLSVL SPPAGPRGAP PAAPYHPFTT HSGYFSSLYP HHQFGPFPHH HSYPEQEIVN LFIPTQAVGA IIGKKGAHIK QLARFAGASI KIAPAEGPDV SERMVIITGP PEAQFKAQGR IFGKLKEENF FNPKEEVKLE AHIRVPSSTA GRVIGKGGKT VNELQNLTSA EVIVPRDQTP DENEEVIVRI IGHFFASQTA QRKIREIVQQ VKQQEQKYPQ GVASQRSK

Target Information

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5` UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.