Thermo Fisher Scientific HSP90 Monoclonal Antibody (MBH90AB)
HSP90 단백질을 인식하는 Thermo Fisher Scientific의 MBH90AB 단클론 항체로, Western blot과 IHC에 적합합니다. 인간, 마우스, 소 등 다양한 종에서 반응하며, Protein A로 정제된 고순도 액상 제품입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Publications: View 3 publications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
- Publications: View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse |
| Published Species | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MBH90AB |
| Immunogen | Peptide corresponding to the sequence EEVHHGEEEVEC within N-terminal part of human Hsp90 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155433 |
Product Specific Information
This antibody recognizes the epitope EEEVE within the N-terminal part of ubiquitously expressed Hsp90 alpha and Hsp90 beta intracellular proteins, with calculated molecular weights of 84.7 kDa and 83.3 kDa, respectively. Under reducing SDS-PAGE conditions, they migrate as 90 kDa bands.
Target Information
HSP90 proteins are highly conserved molecular chaperones involved in signal transduction, protein folding, degradation, and morphologic evolution. They interact with cochaperones to fold newly synthesized proteins or refold denatured proteins after stress.
There are two major cytosolic forms: HSP90AA1 (inducible) and HSP90AB1 (constitutive), as well as mitochondrial variants (Chen et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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