Thermo Fisher Scientific Fumarase Monoclonal Antibody (8F12BB5)
Thermo Fisher Scientific의 Fumarase Monoclonal Antibody (8F12BB5)는 IHC, ICC/IF, IP 등 다양한 응용에 적합한 고특이성 항체입니다. Mouse IgG2a 형식의 단클론 항체로, 1 mg/mL 농도의 액상 제품이며 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A21981
- 판매단위
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8F12BB5 |
| Immunogen | Purified proteins from bovine liver, bovine heart, porcine heart |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| RRID | AB_2535893 |
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended forms, differing only in the translation start site used. The extended form is targeted to the mitochondrion, where removal of the extension yields the same form as in the cytoplasm. This enzyme functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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