Thermo Fisher Scientific EHMT1 Polyclonal Antibody
EHMT1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EHMT1 (Accession Q9H9B1), corresponding to amino acid residues C842–L892 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899369 |
Product Specific Information
Antibody detects endogenous levels of total EHMT1.
Target Information
EHMT1 (also known as EUHMTASE1) is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro.
H3 Lys-9 methylation serves as an epigenetic transcriptional repression tag by recruiting HP1 proteins to methylated histones.
EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1.
During the G0 phase, it may contribute to silencing MYC- and E2F-responsive genes, indicating a role in the G0/G1 transition of the cell cycle.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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