Thermo Fisher Scientific SPZ1 Monoclonal Antibody (3D12)
SPZ1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 3D12). Western blot과 ELISA에 적합하며, Human 및 Mouse 반응성 보유. Affinity chromatography로 정제된 액상 형태로, 연구용으로만 사용.
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- H00084654-M08
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D12 |
| Immunogen | SPZ1 (NP_115956.2, 1–430 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASSAKSAEM PTISKTLNPT PDPHQEYLDP RITIALFEIG SHSPSSWGSL PFLKNSSHQV TEQQTAQKFN NLLKEIKDIL KNMAGFEEKI TEAKELFEET NITEDVSAHK ENIRGLDKIN EMLSTNLPVS LAPEKEDNEK KQEMILETNI TEDVSAHKEN IRGLDKINEM LSTNLPVSLA PEKEDNEKKQ QMIMENQNSE NTAQVFARDL VNRLEEKKVL NETQQSQEKA KNRLNVQEET MKIRNNMEQL LQEAEHWSKQ HTELSKLIKS YQKSQKDISE TLGNNGVGFQ TQPNNEVSAK HELEEQVKKL SHDTYSLQLM AALLENECQI LQQRVEILKE LHHQKQGTLQ EKPIQINYKQ DKKNQKPSEA KKVEMYKQNK QAMKGTFWKK DRSCRSLDVC LNKKACNTQF NIHVARKALR GKMRSASSLR
Target Information
Spermatogenic leucine zipper protein 1 (SPZ1)는 basic helix-loop-helix (bHLH) 계열 전사 인자로, 고환과 부고환에서 특이적으로 발현됩니다. SPZ1은 MAPK (ERK1/2) 신호 경로 하류에서 작용하여 세포 증식과 종양 형성을 촉진하며, proliferating cell nuclear antigen (PCNA) 프로모터와의 상호작용을 통해 PCNA 유전자 발현을 증가시킵니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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