Thermo Fisher Scientific UNC5B Polyclonal Antibody
Human UNC5B 단백질을 인식하는 Goat Polyclonal 항체로 Western blot에 적합. 내부 서열(aa629-643)에서 유래한 펩타이드로 면역화됨. 0.5 mg/mL 농도의 액상형 제품이며 TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide를 포함. -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SARDWIFQLKTQAHQ, from the internal region of UNC5B (aa629–643) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2554597 |
Product Specific Information
- This antibody is predicted to react with mouse, rat, dog, pig, and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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