Thermo Fisher Scientific KANK1 Polyclonal Antibody
KANK1 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 사용 가능. 1 mg/mL 액상 형태로 제공되며, 4°C에서 보관. 세포골격 형성 및 종양 억제 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1302 and 1352 of human KN motif and ankyrin repeat domains 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization.
KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution.
KANK1 is ubiquitously expressed and localizes to the cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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