Thermo Fisher Scientific PGAM1 Polyclonal Antibody
PGAM1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간에 반응하며, 예측 반응종은 원숭이, 소, 개구리 등입니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 191–254 of PGAM1 (Uniprot ID: P18669) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153927 |
Product Specific Information
- Recommended positive control: 293T cells
- Predicted reactivity: Xenopus laevis (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PGAM1 (Phosphoglycerate Mutase 1) is a key enzyme in glycolysis, catalyzing the reversible conversion of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA). It functions as a dimeric enzyme with tissue-specific isoforms: MM (muscle), BB (brain), and MB (hybrid).
Mutations in PGAM1 are associated with glycogen storage disease type X. Recombinant human PGAM1 protein with an N-terminal His-tag was expressed in E. coli and purified using conventional chromatography.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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