Thermo Fisher Scientific SMARCB1/SNF5 Polyclonal Antibody
SMARCB1/SNF5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 액상 형태로 1 mg/mL 농도이며, 4°C 보관 및 Wet ice 배송. FFPE 조직에서 citrate buffer(pH 6.0) 전처리 권장.
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Thermo Fisher Scientific SMARCB1/SNF5 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of Human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (sucrose nonfermenting 5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, Chicken, and Bovine
Target Information
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner.
Brm (SNF2alpha) and Brg-1 (SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex.
Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170 form the functional core of the complex.
Addition of Ini1, BAF155, and BAF170 to Brg-1 increases remodeling activity.
Other subunits play regulatory roles.
hSNF2L and hSNF2H are homologs of Drosophila ISWI, present in chromatin remodeling complexes such as NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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